@article {Lopez-Espinosa:January 2007:0265-203X:95,
	author = "Lopez-Espinosa, M. -J.",
	author = "Granada, A.",
	author = "Araque, P.",
	author = "Molina-Molina, J. -M.",
	author = "Puertollano, M. -C.",
	author = "Rivas, A.",
	author = "Fernandez, M.",
	author = "Cerrillo, I.",
	author = "Olea-Serrano, M. -F.",
	author = "Lopez, C.",
	author = "Olea, N.",
	title = "Oestrogenicity of paper and cardboard extracts used as food containers",
	journal = "Food Additives and Contaminants",
	volume = "24",
	year = "January 2007",
	abstract = "Bisphenol-A (BPA), dibutyl phthalate (DBP), and di-2-ethylhexyl phthalate (DEHP), which are common chemical residues in food-packaging materials, were investigated in paper and cardboard containers used for take-away food. The oestrogenicity of aqueous extracts was tested in E-Screen bioassay and analysis carried out by high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC/MS). Oestrogenicity was demonstrated in 90% of extracts (geometric mean [GM] = 11.97 pM oestradiol equivalents g-1). DEHP, DBP, and BPA (GM = 341.74, 37.59, and 2.38 ng g-1 of material) were present in 77.50, 67.50, and 47.50% of samples, respectively. In bivariate analyses, no significant association was found between the levels of these chemicals and oestrogenicity in cardboard/paper extracts. A close-to-significant association was found between oestrogenicity and DBP (β = 1.25; p = 0.06) in paper extracts, which reached statistical significance in multivariate analysis (β = 1.61; p = 0.03). Paper and cardboard used in food packaging may contribute to the inadvertent exposure of consumers to endocrine-disrupting chemicals.",
	pages = "95-102(8)",
	url = "http://www.ingentaconnect.com/content/tandf/tfac/2007/00000024/00000001/art00010"
	doi = "doi:10.1080/02652030600936375"
}