@article {Bruno:20 July 2006:1478-6419:827,
	author = "Bruno, M.",
	author = "Fiori, M.",
	author = "Mattei, D.",
	author = "Melchiorre, S.",
	author = "Messineo, V.",
	author = "Volpi, F.",
	author = "Bogialli, S.",
	author = "Nazzari, M.",
	title = "ELISA and LC-MS/MS methods for determining cyanobacterial toxins in blue-green algae food supplements",
	journal = "Natural Product Research",
	volume = "20",
	year = "20 July 2006",
	abstract = "The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fischeri bioassay. Further analyses with ELISA and LC-MS/MS methods revealed the presence of four microcystin (MC) analogues, MC-LR, -YR, -LA, -RR and two demethylated forms of MC-RR. The highest total microcystin content was 4.5 and 1.4µgg −1 in pills and capsules, respectively. The ELISA measurements, compared to the LC-MS/MS analyses, showed significantly lower concentrations of microcystins in pills, this confirming a possible ELISA underestimate of mixed microcystins, due to different sensitivities for some toxic analogues.",
	pages = "827-834(8)",
	url = "http://www.ingentaconnect.com/content/tandf/gnp/2006/00000020/00000009/art00008"
	doi = "doi:10.1080/14786410500410859"
}