A facile and chemoselective cleavage of trityl ethers by indium tribromide

Authors: Yadav, J.S.; Reddy, B. V. Subba; Srinivas, R.; Maiti, A.

Source: Journal of Chemical Research, Volume 2001, Number 12, December 2001 , pp. 528-529(2)

Publisher: Science Reviews 2000 Ltd

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Abstract:

Trityl ethers are chemoselectively deprotected to the corresponding alcohols in high yields by a catalytic amount of indium tribromide in aqueous acetonitrile. The method is compatible with various functional groups such as acetonides, acetates, benzoates, olefins, carbamates, esters and ethers present in the substrate.

Keywords: trityl ethers; indium tribromide; chemoselective cleavage

Document Type: Research article

DOI: 10.3184/030823401103168767

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