@article {McCain:June 2006:0003-7028:663,
author = "McCain, S.T.",
author = "Gehm, M.E.",
author = "Wang, Y.",
author = "Pitsianis, N.P.",
author = "Brady, D.J.",
title = "Coded Aperture Raman Spectroscopy for Quantitative Measurements of Ethanol in a Tissue Phantom",
journal = "Applied Spectroscopy",
volume = "60",
year = "June 2006",
abstract = "Coded aperture spectroscopy allows for sources of large étendue to be efficiently coupled into dispersive spectrometers by replacing the traditional input slit with a patterned mask. We describe a coded aperture spectrometer optimized for Raman spectroscopy of diffuse sources, (e.g., tissue). We provide design details of the Raman system, along with quantitative estimation results for ethanol at non-toxic levels in a lipid tissue phantom. With 60 mW of excitation power at 808 nm, leave-one-out and blind cross-validation of partial least squares (PLS) regression models achieve r2 > 0.98. Leave-one-out cross-validation demonstrates prediction errors of, <15% at the common legal limit for intoxication (17.4 mmol/L = 0.08% by vol) and the best blind cross-validation achieves <12% error at this concentration.",
pages = "663-671(9)",
url = "http://www.ingentaconnect.com/content/sas/sas/2006/00000060/00000006/art00015"
doi = "doi:10.1366/000370206777670693"
}