@article {Kim:1 February 1999:0022-3573:221,
	author = "Kim H-M.",
	author = "Cho S-H.",
	title = "Lavender Oil Inhibits Immediate-type Allergic Reaction in Mice and Rats",
	journal = "Journal of Pharmacy and Pharmacology",
	volume = "51",
	year = "1 February 1999",
	abstract = "We studied the effects of lavender oil on mast cell-mediated immediate-type allergic reactions in mice and rats.<P></P>Lavender oil (1:500, 1:100, 1:10, 1:1, 1:0) inhibited concentration-dependently mast cell-dependent ear swelling response induced by compound 48/80 in mice by both topical and intradermal application. Lavender oil (1:500, 1:100, 1:10, 1:1, 1:0) inhibited concentration-dependently passive cutaneous anaphylaxis induced by anti-dinitrophenyl (DNP) IgE in rats by both topical and intradermal application.<P></P>Lavender oil (1:500, 1:100, 1:10, 1:1, 1:0) also inhibited concentration-dependently the histamine release from the peritoneal mast cells by compound 48/80 or anti-DNP IgE. Moreover, lavender oil (1:1000, 1:100, 1:10, 1:0) had a significant inhibitory effect on anti-DNP IgE-induced tumour necrosis factor-<IMG SRC="/iso-ents/isogrk32/alpha-s.gif" ALT="alpha"> secretion from peritoneal mast cells.<P></P>These results indicate that lavender oil inhibits immediate-type allergic reactions by inhibition of mast cell degranulation in-vivo and in-vitro.",
	pages = "221-226(6)",
	url = "http://www.ingentaconnect.com/content/rpsgb/jpp/1999/00000051/00000002/art00017"
	doi = "doi:10.1211/0022357991772178"
}