IngentaConnect A report on the activity and clinical outcomes of renal non-heart...

Authors: Brook, Nicholas R¹; Waller, Julian R¹; Richardson, Amanda C¹; Andrew Bradley, J²; Andrews, Peter A³; Koffman, Geoff³; Gok, Mohammed⁴; Talbot, David⁴; Nicholson, Michael L¹

Source: Clinical Transplantation, Volume 18, Number 6, December 2004 , pp. 627-633(7)

Publisher: Blackwell Publishing

Abstract:

Brook NR, Waller JR, Richardson AC, Bradley JA, Andrews PA, Koffman G, Gok M, Talbot D, Nicholson ML. A report on the activity and clinical outcomes of renal non-heart beating donor transplantation in the United Kingdom.

Clin Transplant 2004 DOI: 10.1111/j.1399-0012.2004.00287.x

The use of kidneys from non-heart beating donors (NHBDs) presents a paradox; whilst they provide more organs for transplantation, there is an increased risk of poor graft outcome, particularly in the short term. This study has highlighted the difference in early graft function and late graft survival between NHBD kidneys with short (controlled) and long (uncontrolled) warm ischaemic times. Whilst it would seem that it is preferable to use controlled donors only, their numbers are small. By employing a rational approach to the use of each of these types of kidney, such as structured viability assessment and risk analysis, it may be that the results of uncontrolled NHBD can be improved.

Keywords: allograft survival; delayed graft function; kidney transplantation; non-heart beating donor; primary non-function

Document Type: Review article

DOI: 10.1111/j.1399-0012.2004.00287.x

Affiliations: 1: Division of Transplant Surgery, University of Leicester, Leicester, UK 2: Department of Surgery, University of Cambridge School of Clinical Medicine, Cambridge, UK 3: Department of Surgery, SW Thames Renal Transplantation Unit, London, UK 4: Renal and Liver Transplant Unit, Freeman Hospital, Newcastle-upon-Tyne, UK

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.39 plus tax Refund Policy