A life without pain? Hedonists take note

Author: Young1

Source: Clinical Genetics, Volume 73, Number 1, January 2008 , pp. 31-33(3)

Publisher: Blackwell Publishing

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Abstract:

An SCN9A channelopathy causes congenital inability to experience pain

Cox et al. (2006)

Nature 444: 894-898

Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

Goldberg et al. (2007)

Clin Genet 71: 311-319

A stop codon mutation in SCN9A causes lack of pain sensation

Ahmad et al. (2007)

Hum Mol Genet 16: 2114-2121

`We cannot learn without pain.'- Aristotle

Document Type: Research article

DOI: 10.1111/j.1399-0004.2007.00921.x

Affiliations: 1: Centre for Molecular Medicine and Therapeutics, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada, Email: fyoung@cmmt.ubc.ca

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