IngentaConnect Five-year risk of progression of primary angle closure to primary...

Authors: Thomas, Ravi¹; Parikh, Rajul²; Muliyil, Jayaprakash³; Kumar, Rajesh S.²

Source: Acta Ophthalmologica Scandinavica, Volume 81, Number 5, October 2003 , pp. 480-485(6)

Abstract:

. Objective:

To report the 5-year progression to primary angle closure glaucoma (PACG) in a population-based cohort of primary angle closure (PAC) subjects. Methods:

A total of 37 patients diagnosed as PAC during a population-based study in 1995 were invited for re-examination in 2000. Patients underwent a complete ophthalmic examination including ocular biometry. Progression to PACG was based on optic disc damage and field defects on automated perimetry. Results:

In all, 28 of 32 PAC subjects who could be contacted presented for examination. Eight (28.5%; 95% CI 12-45%) had progressed to PACG; two of seven with appositional and six of 21 with synechial closure. All were advised laser peripheral iridotomy (LPI) in 1995; one of the nine who underwent LPI progressed compared to seven of 19 who refused LPI. Four of those originally diagnosed with appositional closure developed peripheral anterior synechiae. One eye of a person previously diagnosed with appositional PAC was reclassified as a primary angle closure suspect (PACS). There was no significant difference in biometric parameters between those who progressed and those who did not. None developed acute PACG or blindness due to glaucoma. Conclusion:

In this population-based study of primary angle closure, the 5-year incidence of PACG was eight patients (28.5%; 95% CI 12-45%). We were unable to identify any features that predicted progression.

Keywords: primary angle closure; primary angle closure glaucoma; population-based; progression; laser peripheral iridotomy

Document Type: Research article

DOI: 10.1034/j.1600-0420.2003.00135.x

Affiliations: 1: LV Prasad Eye Institute, Hyderabad, India 2: Department of Ophthalmology, Christian Medical College Hospital, Vellore, India 3: Department of Community Medicine, Christian Medical College Hospital, Vellore, India

You have access to the full text article on a website external to Ingentaconnect.

Please click here to view this article on InterScience.

You may be required to register and activate access on InterScience before you can obtain the full text. If you have any queries please contact onlinehelp@oxon.blackwellpublishing.com

Five-year risk of progression of primary angle closure to primary angle closure glaucoma: a population-based study