@article {Lindberg:January 2006:0001-690X:54, author = "Lindberg, C.", author = "Koefoed, P.", author = "Hansen, E. S.", author = "Bolwig, T. G.", author = "Rehfeld, J. F.", author = "Mellerup, E.", author = "Jorgensen, O. S.", author = "Kessing, L. V.", author = "Werge, T.", author = "Haugbol, S.", author = "Wang, A. G.", author = "Woldbye, D. P. D.", title = "No association between the 399 CT polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population", journal = "Acta Psychiatrica Scandinavica", volume = "113", year = "January 2006", abstract = "Lindberg C, Koefoed P, Hansen ES, Bolwig TG, Rehfeld JF, Mellerup E, Jørgensen OS, Kessing LV, Werge T, Haugbøl S, Wang AG, Woldbye DPD. No association between the –399 C>T polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population. <br />Acta Psychiatr Scand 2005: 1–5. © 2005 Blackwell Munksgaard. Objective: 

A polymorphism in the promoter region of the NPY gene at position −399 C>T was recently reported to be associated with schizophrenia in a Japanese population and with treatment refractory unipolar depression in a Swedish population. The objective of this study was to investigate potential associations between the polymorphism and three psychiatric disorders in a Danish population. Method: 

We investigated the occurrence of the polymorphism in patients with schizophrenia (n = 291), unipolar depression (n = 256) and panic disorder (n = 142) compared with controls (n = 716). Results: 

We detected the polymorphism −399 C>T at a frequency of 48% in controls. No significant differences were found between genotype or allele frequencies in controls vs. the patient groups. Conclusion: 

The lack of association between the −399 C>T polymorphism and schizophrenia, unipolar depression or panic disorder, respectively, suggests that the polymorphism is not involved in the etiology of these disorders in the Danish population.", pages = "54-58(5)", url = "http://www.ingentaconnect.com/content/mksg/acp/2006/00000113/00000001/art00009" doi = "doi:10.1111/j.1600-0447.2005.00648.x" }