@article {Samuelsson:January 2006:0001-690X:44, author = "Samuelsson, M.", author = "Jokinen, J.", author = "Nordstrom, A.-L.", author = "Nordstrom, P.", title = "CSF 5-HIAA, suicide intent and hopelessness in the prediction of early suicide in male high-risk suicide attempters", journal = "Acta Psychiatrica Scandinavica", volume = "113", year = "January 2006", abstract = "Samuelsson M, Jokinen J, Nordström A-L, Nordström P. CSF 5-HIAA, suicide intent and hopelessness in the prediction of early suicide in male high-risk suicide attempters. <br />Acta Psychiatr Scand 2005: 1–4. © 2005 Blackwell Munksgaard. Objective:
To study the predictive value of the Beck Suicide Intent Scale (SIS), the Beck Hopelessness Scale (BHS) and of 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid for future early suicide in a group of high-risk male suicide attempters. Method: Fifteen consecutive male suicide attempters admitted to a psychiatric ward at the Karolinska Hospital, who were not receiving any treatment with antidepressants were diagnosed according to DSM-III, assessed with SIS and BHS and submitted to lumbar puncture. All patients were followed up for cause of death. Results: Five early suicides (within 2 years) were identified. Mean cerebrospinal fluid (CSF) 5-HIAA differed between suicides and survivors. Low CSF 5-HIAA was identified in those who committed early suicide. Neither the Suicide Intent Score nor the Hopelessness Score distinguished suicides from survivors. Conclusion: In high suicide risk hospitalized male psychiatric patients CSF 5-HIAA may be a better predictor of early suicide after attempted suicide than SIS or BHS.", pages = "44-47(4)", url = "http://www.ingentaconnect.com/content/mksg/acp/2006/00000113/00000001/art00007" doi = "doi:10.1111/j.1600-0447.2005.00639.x" }