Development of neuropsychiatric symptoms in poststroke patients: a cross-sectional study
Authors: Angelelli P.; Paolucci S.1; Bivona U.; Piccardi L.; Ciurli P.1; Cantagallo A.2; Antonucci G.; Fasotti L.3; Di Santantonio A.4; Grasso M.G.1; Pizzamiglio L.
Source: Acta Psychiatrica Scandinavica, Volume 110, Number 1, July 2004 , pp. 55-63(9)
Publisher: Blackwell Publishing
Abstract:
Angelelli P, Paolucci S, Bivona U, Piccardi L, Ciurli P, Cantagallo A, Antonucci G, Fasotti L, Di Santantonio A, Grasso MG, Pizzamiglio L. Development of neuropsychiatric symptoms in poststroke patients: a cross-sectional study. Acta Psychiatr Scand 2004: 110: 5563. © Blackwell Munksgaard 2004. Objective: The study aimed to characterize neuropsychiatric symptomatology and its evolution in a large group of poststroke patients during their first year. Method: The Neuropsychiatric Inventory (NPI) was administered to a sample of 124 poststroke patients, divided into three independent groups on the basis of time from stroke (2, 6 and 12 months). The controls were 61 healthy subjects. Results: A wide range of neuropsychiatric symptoms was found significant in the poststroke population: mostly depression (61%), irritability (33%), eating disturbances (33%), agitation (28%), apathy (27%) and anxiety (23%). Modifications in terms of greater depression, anxiety, irritability and eating disturbances evolved in the year following stroke. Other symptoms were significantly present depending on time from stroke. Clear relations with other clinical and demographic variables were also found. Conclusion: Neuropsychiatric symptoms constitute an important part of comorbidity in stroke patients; thus, suitable assessment tools may improve clinical understanding of these patients.Keywords: cross-sectional study; stroke; neuropsychiatric symptoms; neuropsychological disorders; depression; irritability
Document Type: Research article
DOI: 10.1111/j.1600-0447.2004.00297.x
Affiliations: 1: Foundation IRCCS Santa Lucia, Rome, Italy 2: Department of Rehabilitation, Hospital and University of Ferrara, Ferrara, Italy 3: Sint Maartenskliniek, Nijmegen, The Netherlands 4: Cognitive Neuroscience Center, Hospital of Cesena, Cesena, Italy

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