@article {Munch:January 2007:0256-7040:67,
	author = "Munch, Tina",
	author = "Bech-Azeddine, Rachid",
	author = "Boegeskov, Lars",
	author = "Gjerris, Flemming",
	author = "Juhler, Marianne",
	title = "Evaluation of the lumbar and ventricular infusion test in the diagnostic strategy of pediatric hydrocephalus and the therapeutic implications",
	journal = "Child's Nervous System",
	volume = "23",
	year = "January 2007",
	abstract = "To evaluate the infusion test as a diagnostic tool behind the choice of intervention in pediatric hydrocephalus.<P></P>Intracranial pressure (ICP) measurement and infusion test were performed intraventricularly, by lumbar route, or combined in 40 consecutive children as a part of the standard diagnostic program in 1996-1999.<P></P>The median age was 18.5 months, ranging from 2 weeks to 13 years. In the subgroup of patients with radiological aqueductal stenosis (<I>N</I>=14), mean lumbar/intraventricular ICP was 13 (3-35)/10 (2-27). Mean lumbar/ventricular <I>R</I> <SUB>out</SUB> were 18 (4-49)/17 (6-37). For patients with radiological communication between the third and fourth ventricles (<I>N</I>=14), the mean lumbar/intraventricular ICP was 11 (7-17)/9 (1-16). Mean lumbar/ventricular <I>R</I> <SUB>out</SUB> were 8 (3-11)/8 (4-12). A total of 13 patients had a shunt insertion, 10 had an endoscopic third ventriculostomy (ETV), 5 had endoscopic fenestration of a cyst, and 12 had no surgery. Of the patients initially treated with EVT, 50% had a shunt insertrion shortly after. For communicating hydrocephalus, 75% of the patients initially not operated based on normal <I>R</I> <SUB>out</SUB> values ended up having a shunt insertion.<P></P> <I>R</I> <SUB>out</SUB> has doubtful value as an indicator for conducting an operation or not and in the choice between EVT and shunt in chiladren. This should be interpreted in the light of a growing understanding of hydrocephalus on a molecular level.",
	pages = "67-71(5)",
	url = "http://www.ingentaconnect.com/content/klu/381/2007/00000023/00000001/00000186"
	doi = "doi:10.1007/s00381-006-0186-4"
}