@article {Idris:January 2007:1027-3719:91,
	author = "Idris, M.N.A.",
	author = "Sokrab, T-E.O.",
	author = "Arbab, M.A.R.",
	author = "Ahmed, A.E.M.",
	author = "El Rasoul, H.",
	author = "Ali, S.",
	author = "Elzubair, M.A.",
	author = "Mirgani, S.M.",
	title = "Tuberculoma of the brain: a series of 16 cases treated with anti-tuberculosis drugs",
	journal = "The International Journal of Tuberculosis and Lung Disease",
	volume = "11",
	year = "January 2007",
	abstract = "OBJECTIVES: To describe the clinical presentation, radiological findings and outcome of treatment with anti-tuberculosis drugs in 16 cases of intracranial tuberculoma.<P></P>DESIGN: Consecutive cases admitted with tuberculoma to the National Center for Neurological Diseases in Khartoum, Sudan, were included in the study. The diagnosis was based on clinical and neuro-imaging features and response to anti-tuberculosis treatment. Histopathology of material from the brain or other extracranial tissues was available in seven cases.<P></P>RESULTS AND CONCLUSIONS: The commonest presenting features were headache (100%), generalized convulsions (68.7%) and hemiparesis (56.2%). Computerised axial tomography/magnetic resonance imaging (CT/MRI) showed single or multiple lesions that showed intense contrast enhancement and perilesional edema. The lesions completely cleared on anti-tuberculosis treatment in the majority of survivors (13/15). Partial clearance of lesion was associated with late presentation, multiple large lesions and advanced miliary disease. We advocate early empirical trial of anti-tuberculosis drugs for intracranial tuberculoma even after a presumptive diagnosis, particularly in areas where the infection is endemic.",
	pages = "91-95(5)",
	url = "http://www.ingentaconnect.com/content/iuatld/ijtld/2007/00000011/00000001/art00015"
}