@article {T.:June 2000:1027-3719:570, author = "T. Rikimaru", author = "M. Kondo", author = "S. Kondo", author = "K. Oizumi", title = "Efficacy of common antiseptics against mycobacteria", journal = "The International Journal of Tuberculosis and Lung Disease", volume = "4", year = "June 2000", abstract = "SETTING AND OBJECTIVE: Antiseptics are frequently used to prevent mycobacterial infection; however, the reported activities of a number of antiseptics against mycobacteria are not always consistent. The aim of this study was to determine those antiseptics that are useful against mycobacteria.

dESIGN: Evaluation of antiseptic activity against mycobacteria in vitro.

RESULTS: The effects of different antiseptics on mycobacteria (Mycobacterium avium, M. kansasii and M. tuberculosis) were examined. At concentrations of 0.05%, povidone-iodine (PVP-I) killed 99% or more of all strains tested within 15 seconds, while 0.5% chlorhexidine gluconate and 0.1% benzalkonium chloride showed no bactericidal activity against mycobacteria. M. kansasii and M. tuberculosis were killed after exposure to cresol for 60 seconds at concentrations of 1.0%, but M. avium was unaffected even after 60 seconds. While M. kansasii and M. tuberculosis were killed by treatment with 2.0% glutaraldehyde for 5 minutes, M. avium was highly resistant to this agent.

CONCLUSION: PVP-I seems to be a useful antiseptic against mycobacteria. The measured activity of antiseptics should be interpreted carefully, due to the potential for interference by artifacts.", pages = "570-576(7)", url = "http://www.ingentaconnect.com/content/iuatld/ijtld/2000/00000004/00000006/art00013" }