@article {Tano:December 2003:1473-7167:741, author = "Tano, Benoit", author = "Pathak, Dev", author = "Hoffmann, Stephen", title = "Cost-effectiveness of Advair: fluticasone propionate and salmeterol combination", journal = "Expert Review of Pharmacoeconomics and Outcomes Research", volume = "3", year = "December 2003", abstract = "The National Heart, Lung and Blood Institute guidelines for the treatment of asthma suggest that inhaled corticosteroids, with the addition of a long-acting bronchodilator, may be the most effective long-term control medication for asthma. Five inhaled corticosteroids are approved for use in the USA, including beclomethasone dipropionate, budesonide, flunisolide, triamcinolone acetonide and fluticasone propionate. Fluticasone propionate (Flixotide®) and the long-acting β2 agonist salmeterol (Serevent®), are now available in the USA together in an easy to use dry powder inhaler Advair®. The cost-effectiveness of this combination in the treatment of persistent asthma is reviewed. This review evaluates all the cost-effectiveness studies comparing fluticasone propionate and salmeterol from two separate inhalers or one single inhaler available in the literature. Cost-effectiveness was compared with inhaled corticosteroids alone, leukotriene receptor antagonists and other combination therapies in patients with persistent asthma.", pages = "741-747(7)", url = "http://www.ingentaconnect.com/content/ftd/erp/2003/00000003/00000006/art00010" doi = "doi:10.1586/14737167.3.6.741" }