Office-Based Cryoablation of Breast Fibroadenomas with Long-Term Follow-up
Authors: Kaufman, Cary S.; Littrup, Peter J.1; Freeman-Gibb, Laurie A.2; Smith, J. Stanley3; Francescatti, Darius4; Simmons, Rache5; Stocks, Lewis H.6; Bailey, Lisa7; Harness, Jay K.7; Bachman, Barbara A.8; Henry, C. Alan9
Source: The Breast Journal, Volume 11, Number 5, September 2005 , pp. 344-350(7)
Publisher: Blackwell Publishing
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Abstract:
: Approximately 10% of women will experience a breast fibroadenoma in their lifetime. Cryoablation is a new treatment that combines the better attributes of the current standards: surveillance and surgery. It is a minimally invasive office-based procedure that is administered without the use of general anesthesia, involving minimal patient discomfort and little to no scarring. This work aimed to establish the long-term (2–3 years) efficacy, safety, and satisfaction of the procedure, as well as the impact of cryoablation on mammogram and ultrasound images. Thirty-seven treated fibroadenomas were available for assessment with an average follow-up period of 2.6 years. Of the original 84% that were palpable prior to treatment, only 16% remained palpable to the patient as of this writing. Of those fibroadenomas that were initially
2.0 cm in size, only 6% remained palpable. A median volume reduction of 99% was observed with ultrasound. Ninety-seven percent of patients and 100% of physicians were satisfied with the long-term treatment results. Mammograms and ultrasounds showed cryoablation produced no artifact that would adversely affect interpretation. Cryoablation for breast fibroadenomas has previously been reported as safe and effective both acutely and at the 1-year follow-up mark, and thus has been implemented as a treatment option. At long-term follow-up, cryoablation as a primary therapy for breast fibroadenomas demonstrates progressive resolution of the treated area, durable safety, and excellent patient and physician satisfaction. The treatment is performed in an office setting rather than an operating room, resulting in a cost-effective and patient-friendly procedure. Cryoablation should be considered a preferred option for those patients desiring definitive therapy for their fibroadenomas without surgical intervention.
Keywords: ablation; breast biopsy; breast surgery; breast tumor; cryoablation; fibroadenoma; minimally invasive; office procedure
Document Type: Research article
DOI: 10.1111/j.1075-122X.2005.21700.x
Affiliations: 1: Wayne State University, Detroit, Michigan; 2: Karmanos Cancer Institute, Detroit, Michigan; 3: Hershey Medical Center of the Pennsylvania State University, Hershey, Pennsylvania; 4: Rush University, Chicago, Illinois; 5: Weill Medical College of Cornell University, New York, New York; 6: Executive Surgical Center, Raleigh, North Carolina; 7: Alta Bates Summit Medical Center, Oakland, California; and 8: University of Washington and the Bellingham Breast Center, Bellingham, Washington; 9: Breast Care Specialists of the Blue Ridge, Roanoke, Virginia
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