@article {Yoshimura:October 2001:1323-1316:543, author = "Yoshimura, Reiji", author = "Kakihara, Shingo", author = "Soya, Atsushi", author = "Ueda, Nobuhisa", author = "Shinkai, Koji", author = "Nakamura, Jun", title = "Effect of clonazepam treatment on antipsychotic drug-induced Meige syndrome and changes in plasma levels of GABA, HVA, and MHPG during treatment", journal = "Psychiatry and Clinical Neurosciences", volume = "55", year = "October 2001", abstract = "

We demonstrated the effect of clonazepam (2 mg/day) on Meige syndrome in two schizophrenic patients under continuous treatment with antipsychotic drugs, and changes in the plasma levels of γ-aminobutyric acid (GABA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG) in these cases. The plasma levels of HVA and MHPG during treatment with clonazepam were decreased in the responder, while not changed in the non-responder to clonazepam. A difference between the responder and the non-responder was not found in the plasma GABA levels. These results suggest that hyperactivities of the central dopaminergic and noradrenergic neurones are involved in the pathophysiology of Meige syndrome.", pages = "543-546(4)", url = "http://www.ingentaconnect.com/content/bsc/pcn/2001/00000055/00000005/art00017" }