IngentaConnect Features of Regression in Dermoscopic Diagnosis: A Confounding Fa...

Authors: GIORGI, VINCENZO¹; MASSI, DANIELA²; SALVINI, CAMILLA¹; SESTINI, SERENA¹; CARLI, PAOLO¹

Source: Dermatologic Surgery, Volume 32, Number 2, February 2006 , pp. 282-286(5)

Abstract:

BACKGROUND

In dermoscopy, the presence of regression areas is generally associated with melanocytic lesions and is often considered as a clue of malignancy. However, some lesions included in the differential diagnosis of melanoma may show dermoscopic regression parameters. Regression may indeed be one of the most confounding dermoscopic parameters, as it tends to cover, or rather to destroy, other parameters, thus often hindering a correct diagnosis. OBJECTIVE

We propose to raise the issue of the actual diagnostic role of this parameter. METHODS

We discuss 2 clinical cases (melanoma and basal cell carcinoma) with major dermoscopic regression features. CONCLUSION

Dermoscopic regression parameters should not be regarded as almost pathognomonic signs of melanocytic lesions. Rather, they should be taken into account only after having considered other dermoscopic parameters of greater diagnostic significance, and just as signs, which may better typify the lesion.

The authors have indicated no significant interest with commercial supporters.

Document Type: Research article

DOI: 10.1111/j.1524-4725.2006.32053.x

Affiliations: 1: Department of Dermatology and 2: Department of Human Pathology and Oncology, University of Florence, Florence, Italy

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Features of Regression in Dermoscopic Diagnosis: A Confounding Factor? Two Clinical, Dermoscopic-Pathologic Case Studies