IngentaConnect Does Injection Distance of the Radiocolloid Modify Lymphatic Mapp...

Authors: Martínez-Escribano, Jorge A.¹; Navarro, José L.²; Piñero, Antonio³; Nicolás, Francisco²; Frías, José F.¹; Sánchez-Pedreño, Paloma¹; Parrilla, Pascual³

Source: Dermatologic Surgery, Volume 27, Number 10, October 2001 , pp. 881-884(4)

Publisher: Blackwell Publishing

Abstract:

Background.

An important factor to be considered when performing lymphogammagraphy in melanoma patients is the adequate distance of injection of the radiopharmaceutical from the biopsy excision site or the primary lesion. Objective.

To test the reproducibility of lymphatic mapping in patients with primary cutaneous melanoma who had undergone narrow excisional biopsy by injecting a technetium marker at different distances from the biopsy scar. Methods.

After informed consent, two lymphoscintigraphies were performed on each of 19 melanoma patients, following narrow excisional biopsy. Four aliquots of the radiocolloid were intradermally injected in each procedure, surrounding the biopsy excision site at 1.5 and 0.5 cm, respectively. Results.

Both lymphoscintigraphies showed similar lymph channels and sentinel node(s). Conclusion.

In melanoma patients who have undergone narrow excisional biopsy, lymphoscintigraphy marks with accuracy the sentinel node, at least when the radiopharmaceutical is injected at a distance of less than 1.5 cm from the limits of the biopsy scar.

Document Type: Research article

Affiliations: 1: Departments of Dermatology, 2: Nuclear Medicine, and 3: General Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain

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Does Injection Distance of the Radiocolloid Modify Lymphatic Mapping in Melanoma?