IngentaConnect Steroid hormone receptors in parotid gland cystadenolymphoma (War...

Authors: Teymoortash, A.¹; Lippert, B.M.¹; Werner, J.A.¹

Source: Clinical Otolaryngology & Allied Sciences, Volume 26, Number 5, October 2001 , pp. 411-416(6)

Abstract:

teymoortash a.,lippert b.m.&werner j.a.

(2001) Clin. Otolaryngol. 26, 411-416

Steroid hormone receptors in parotid gland cystadenolymphoma (Warthin's tumour)

The aetiopathogenesis of cystadenolymphoma is mostly unknown. Cystadenolymphomas have a significantly higher incidence in the male than the female population. This might be as a result of endocrine dependency in this kind of tumour. The purpose of the present study was to determine the sex hormone receptor status in cystadenolymphoma. Tissue samples of cystadenolymphoma, pleomorphic adenoma and normal samples of the parotid gland were examined immunohistochemically for oestrogen and progesterone receptors. Progesterone-positive cells could be found in the salivary duct system of normal glands and in the epithelial components of cystadenolymphomas. There was no evidence for the presence of oestrogen receptor in any sample studied. The evidence of progesterone receptors in cystadenolymphoma may implicate a potential role of endocrine factors in the development of this tumour.

Keywords: cystadenolymphoma; Warthin's tumour; steroid receptor; progesterone receptor; oestrogen receptor

Document Type: Research article

Affiliations: 1: Department of Otolaryngology, Head and Neck Surgery, Philipps University, Marburg, Germany

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