IngentaConnect In vivo induced antigen technology (IVIAT)

Authors: Sean M. Rollins¹; Amanda Peppercorn¹; Long Hang¹; Jeffrey D. Hillman; Stephen B. Calderwood; Martin Handfield²; Edward T. Ryan

Source: Cellular Microbiology, Volume 7, Number 1, January 2005 , pp. 1-9(9)

Publisher: Blackwell Publishing

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Abstract:

Summary

In vivo induced antigen technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during human infection. IVIAT is complementary to other techniques that identify genes and their products expressed in vivo. Genes and gene pathways identified by IVIAT may play a role in virulence or pathogenesis during human infection, and may be appropriate for inclusion in therapeutic, vaccine or diagnostic applications.

Document Type: Research article

DOI: 10.1111/j.1462-5822.2004.00477.x

Affiliations: 1: Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA. 2: Center for Molecular Microbiology, Department of Oral Biology, University of Florida, Gainesville, FL, USA.

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