@article {Raymond:February 2007:1198-743X:172,
author = "Raymond, J.",
author = "Armengaud, J.-B.",
author = "Cosnes-Lambe, C.",
author = "Chalumeau, M.",
author = "Bosdure, E.",
author = "Reglier-Poupet, H.",
author = "El Hajje, M.-J.",
author = "Iniguez, J.-L.",
author = "Moulin, F.",
author = "Poyart, C.",
author = "Gendrel, D.",
title = "Pertussis in young infants: apnoea and intra-familial infection",
journal = "Clinical Microbiology & Infection",
volume = "13",
year = "February 2007",
abstract = "This study investigated 41 infants, aged <4 months, who were hospitalised with symptoms compatible with pertussis. Of these, 16 had Bordetella pertussis infection confirmed by real-time PCR. For four of these 16 patients, the initial sample was PCR-negative, but samples collected 5-7 days after the onset of infection were PCR-positive. PCR was also positive with samples from 15/16 families and 20/41 household contacts. Nine of the 20 positive household contacts were asymptomatic. Among the 16 infants with proven pertussis, apnoea was more frequent than in a control group for whom PCR was negative with both children and household contacts (69% vs. 28%). It was concluded that real-time PCR performed with samples from household contacts facilitates the diagnosis of infants suspected clinically of having pertussis, thereby enabling earlier treatment.",
pages = "172-175(4)",
url = "http://www.ingentaconnect.com/content/bsc/clm/2007/00000013/00000002/art00008"
doi = "doi:10.1111/j.1469-0691.2006.01616.x"
}