An unusual reoccurrence of Waldenstrom's macroglobulinemia as pleural effusions that had a discordant response with treatment

Authors: AMIN, C. J.; RABINOWITZ, I.

Source: Clinical & Laboratory Haematology, Volume 27, Number 3, June 2005 , pp. 200-202(3)

Publisher: Blackwell Publishing

Key:

- Free Content

- New Content

- Subscribed Content

- Free Trial Content

Abstract:

Summary

A 77-year-old female with a past medical history of Waldenstrom's macroglobulinemia presented with progressive shortness of breath and a newly diagnosed left pleural effusion. Numerous diagnostic studies were performed on the patient and finally a pleural biopsy confirmed pulmonary involvement of Waldenstrom's macroglobulinemia. As past studies have shown, Waldenstrom's involvement as a pulmonary process is uncommon. Unexpectedly, treatment with rituximab and fludarabine did decrease the patient's serum immunoglobulin M levels, but her pleural effusions never improved.

Keywords: Neoplasm; Waldenstrom macroglobulinemia; pleural effusion; lymphoma; antibodies; monoclonal

Document Type: Research article

DOI: 10.1111/j.1365-2257.2005.00666.x

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.16 plus tax Refund Policy