IgD myeloma with multiple cutaneous plasmacytomas

Authors: PATEL1; CARRINGTON2; BHATNAGAR3; HOUGHTON2; ROUTLEDGE2

Source: Clinical & Laboratory Haematology, Volume 20, Number 1, February 1998 , pp. 53-55(3)

Publisher: Blackwell Publishing

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Abstract:

Extramedullary cutaneous plasmacytoma is an uncommon observation in clinical practice. In most of the cases it is usually an extension of underlying medullary plasmacytoma. This case report describes a patient with IgD myeloma who went into plateau phase following standard intravenous chemotherapy. After more than a year in plateau phase, he developed multiple fleshy nodular lesions in the skin. Biopsy of one of the lesions revealed relapse of myeloma in the skin. His IgD paraprotein remained in plateau phase and the bone marrow showed only 1% plasma cells. The patient has been treated with systemic intravenous chemotherapy followed by local radiotherapy.

Keywords: IgD myeloma; cutaneous plasmacytoma; extramedullary

Document Type: Research article

DOI: 10.1046/j.1365-2257.1998.00085.x

Affiliations: 1: Department of Medicine, Jamaica Hospital Medical Center, Jamaica, New York, USA, 2: Department of Haematology, Hope Hospital, Manchester, UK, 3: Department of Histopathology, Hope Hospital, Manchester, UK

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