Transcatheter Device Occlusion of Multiple Large Pulmonary Arteriovenous Malformations in Two Symptomatic Pediatric Patients

Authors: Ellis, Alexander R.; Hlavacek, Anthony M.; Bandisode, Varsha M.; Ringewald, Jeremy M.

Source: Congenital Heart Disease, Volume 1, Number 6, November/December 2006 , pp. 327-331(5)

Publisher: Blackwell Publishing

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Abstract:

Pulmonary arteriovenous malformations (AVMs) large enough to lead to clinically significant cyanosis are rare in the pediatric population. To date, there has been some experience with transcatheter embolization of pulmonary AVMs in children, primarily with coils or balloons. Herein, we report 2 cases of children who were progressively symptomatic and had physical manifestations of hypoxemia arising from large pulmonary AVMs. Both improved after successful catheter-based placement of multiple occlusion devices (Amplatzer vascular plugs) in the pulmonary arterial segments feeding the AVMs produced a rapid, sustained increase in oxygen saturations, and a subsequent amelioration of their symptoms. This represents the first case series of multiple Amplatzer vascular plugs placed into numerous arteriovenous formations, exclusively in children. This approach represents an additional nonsurgical option for children or adults with symptomatic pulmonary AVMs.

Keywords: Pulmonary Arteriovenous Malformation; AVM; Transcatheter Device Closure; Vascular Plug; Children

Document Type: Research article

DOI: 10.1111/j.1747-0803.2006.00057.x

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