The contribution of Bruce Glick to the definition of the role played by the bursa of Fabricius in the development of the B cell lineage

Authors: Ribatti, D.; Crivellato, E.¹; Vacca, A.²

Source: Clinical & Experimental Immunology, Volume 145, Number 1, July 2006 , pp. 1-4(4)

Publisher: Blackwell Publishing

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Abstract:

Summary

In 1956, Bruce Glick and Timothy Chang reported that the bursa of Fabricius plays an important role in antibody production. Their demonstration that antibody responses are suppressed in the majority of bursectomized chickens became the cornerstone of modern immunology. Bursa research increased considerably during the 1960s and early 1970s.

Keywords: B cell; bursa of Fabricius; history of medicine; immunology; T cell

Document Type: Review article

DOI: 10.1111/j.1365-2249.2006.03131.x

Affiliations: 1: Department of Medical and Morphological Researches, Anatomy Section, University of Udine Medical School, Udine, Italy, and 2: Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy

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