Pyoderma gangrenosum as initial manifestation of Graves' disease

Authors: Livideanu, C.; Lipsker, D.¹; Paul, C.; Juillard, J.; Schubert, B.

Source: Clinical & Experimental Dermatology, Volume 31, Number 5, September 2006 , pp. 659-661(3)

Publisher: Blackwell Publishing

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Abstract:

Summary

Pyoderma gangrenosum (PG) is an uncommon ulcerative condition. It is most commonly associated with inflammatory bowel disease, haematological malignancies and autoimmune disease. We report on two patients have developed PG during the initial course of Graves' disease (GD), prior to treatment of this condition. The lesions completely cleared with treatment by colchicine in the first case and with oral ciclosporin in the second case. The report emphasizes that a diagnostics of PG should be considered in patients with GD and skin ulcers.

Document Type: Research article

DOI: 10.1111/j.1365-2230.2006.02184.x

Affiliations: 1: Dermatology and Venerology Clinic, Place de l'Hôpital, Strasbourg University Hospital, Strasbourg cedex, France

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