Microscopic polyarteritis presenting with skin necrosis in a patient with sickle-cell disease

Authors: Dawe, S. A.; Powell, S. E.; Short, K. A.; Salisbury, J.¹; Roberts, J.²; Creamer, D.

Source: Clinical & Experimental Dermatology, Volume 31, Number 1, January 2006 , pp. 60-62(3)

Publisher: Blackwell Publishing

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Abstract:

Summary

A 20-year-old Caribbean woman with sickle cell anaemia was admitted with a 4-day history of fever and a painful swollen right ankle. She rapidly developed skin necrosis. The differential diagnosis is discussed. This case illustrates the difficulty in identifying the cause of cutaneous necrosis in an acutely ill patient. In our patient, histopathology implicated a vasculitic process, which was subsequently identified as a manifestation of microscopic polyarteritis.

Document Type: Research article

DOI: 10.1111/j.1365-2230.2005.01950.x

Affiliations: 1: Histopathology 2: Breast Surgery, Kings College Hospital, Denmark Hill, London SE5 9RS, UK

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