Cutaneous gangrene due to hyperparathyroidism secondary to chronic renal failure (uraemic gangrene syndrome)

Authors: TÖRÖK, L.¹; KÖZÉPESSY, L.²

Source: Clinical & Experimental Dermatology, Volume 21, Number 1, January 1996 , pp. 75-77(3)

Publisher: Blackwell Publishing

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Abstract:

Cutaneous and subcutaneous gangrene are serious sequelae of secondary or tertiary hyperparathyroidism which may accompany chronic renal failure. Based on analysis of the present typical case and a retrospective survey of similar cases in the literature, we propose the term `uraemic gangrene syndrome' for this association. These skin lesions in chronic renal failure patients represent the most serious clinical manifestation of calciphylaxis, a condition originally described by Selye. The appearance of early skin lesions should be regarded as an indication for subtotal parathyroidectomy.

Document Type: Research article

DOI: 10.1046/j.1365-2230.1996.d01-175.x

Affiliations: 1: Department of Dermatology, 2: Department of Nephrology and Dialysis, County Hospital Bács-Kiskun, Kecskemét, Hungary

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