IngentaConnect Mycosis fungoides associated with unusual epidermal hyperplasia

Authors: PUIG, L.¹; MUSULÉN, E.²; FERNÁNDEZ-FIGUERAS, M.-T.³; MIRALLES, J.¹; SITJAS, D.⁴; DE MORAGAS, J.M.¹

Source: Clinical & Experimental Dermatology, Volume 21, Number 1, January 1996 , pp. 61-64(4)

Publisher: Blackwell Publishing

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Abstract:

A 58-year-old white woman presented with widespread pruritic brownish plaques and hyperpigmented flexural lesions with a velvety appearance. On histopathological examination, the macules were diagnostic of mycosis fungoides, plaque stage, and the flexural lesions showed epidermal hyperplasia with a seborrhoeic keratosis-like appearance. There was intense mucin deposition and marked reduction of elastic fibres in the papillary dermis, as well as a moderately dense dermal lymphoid infiltrate composed of CD4⁺ T cells with occasional atypia and focal epidermotropism.

Document Type: Research article

DOI: 10.1046/j.1365-2230.1996.d01-170.x

Affiliations: 1: Departments of Dermatology, 2: Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona, 3: Department of Pathology, Hospital Universitari Germans Trias i Pujol, Badalona, 4: Department of Dermatology, Hospital de Figueres, Figueres, Spain

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