IngentaConnect Bullous pemphigoida report of 86 cases from Taiwan

Authors: CHANG, Y.T.¹; LIU, H.N.¹; WONG, C.K.¹

Source: Clinical & Experimental Dermatology, Volume 21, Number 1, January 1996 , pp. 20-22(3)

Abstract:

We reviewed 86 cases of bullous pemphigoid and the results were compared with those reported in the literature. Seventy-eight per cent of the patients developed generalized blisters and 22% had localized blisters, including three cases of dyshidrosiform pemphigoid and one case of pretibial pemphigoid. Oral mucosal involvement was noticed in 12.8% of the patients. Fifteen per cent of the patients had internal malignancies but the incidence was not significantly different from the control group. Direct immunofluorescence in our series showed a high positive rate of 98.8%. Indirect immunofluorescence was positive in 48.1% of the 54 patients in whom this was carried out. Peripheral blood eosinophilia was observed in 22.1% of the patients. Prednisolone alone or in combination with immunosuppressive agents was the mainstay of treatment. Treatment side-effects was observed in 33% of the patients. Thirty per cent of the patients had a complete remission after a mean follow-up period of 26.9 months.

Document Type: Research article

DOI: 10.1046/j.1365-2230.1996.d01-161.x

Affiliations: 1: Department of Dermatology, National Yang-Ming University, and Veterans General Hospital, Taipei, Taiwan

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Bullous pemphigoid-a report of 86 cases from Taiwan