Sclerosing panniculitis is associated with pulmonary hypertension in systemic sclerosis

Authors: Jinnin, M.; Ihn, H.; Asano, Y.; Yamane, K.; Yazawa, N.; Tamaki, K.

Source: British Journal of Dermatology, Volume 153, Number 3, September 2005 , pp. 579-583(5)

Publisher: Blackwell Publishing

Key:

- Free Content

- New Content

- Subscribed Content

- Free Trial Content

Abstract:

Summary Background

There have been no reports of patients with sclerosing panniculitis and systemic sclerosis (SSc). Objectives

To evaluate the incidence of sclerosing panniculitis in patients with SSc, and to investigate the clinical features of such cases. Methods

In total, 128 patients with SSc treated at our clinic were investigated retrospectively. Results

SSc patients with sclerosing panniculitis had pulmonary hypertension (PH), especially isolated PH, at a significantly higher incidence than those without. Among the SSc patients with PH, those with sclerosing panniculitis had pulmonary infarctions at a higher incidence than those without. Conclusions

Our results suggest that thrombosis caused by venous hypertension of the leg may be the main cause of PH in patients with SSc and sclerosing panniculitis. Sclerosing panniculitis may be a useful marker of PH in patients with SSc.

Keywords: echocardiogram; pulmonary embolism; pulmonary hypertension; sclerosing panniculitis; systemic sclerosis

Document Type: Research article

DOI: 10.1111/j.1365-2133.2005.06680.x

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.16 plus tax Refund Policy