Malignant transformation of multiple dermal cylindromas

Authors: Durani B.K.; Kurzen H.; Jaeckel A.; Kuner N.; Naeher H.; Hartschuh W.

Source: British Journal of Dermatology, Volume 145, Number 4, October 2001 , pp. 653-656(4)

Publisher: Blackwell Publishing

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Abstract:

Cylindromas are benign tumours arising as small, solitary, slow-growing nodules on the head and neck. Multiple cylindromas may form a ‘turban tumour’ in the autosomal dominant Brooke–Spiegler syndrome. We report two unusual cases of multiple cylindromas with transformation into cylindrocarcinomas. The first patient, a 63-year-old white woman, developed a cylindrocarcinoma on pre-existing multiple cylindromas on her right shoulder. Eight months after resection she developed a lymph node metastasis in the right axilla. The second patient, a 68-year-old white woman, presented with multiple cylindromas of the scalp. One of these transformed into a cylindrocarcinoma, infiltrating the dura mater, with local recurrence 2 years after incomplete resection and postoperative radiation.

Keywords: carcinoma; cylindroma; metastasis; skin

Document Type: Research article

DOI: 10.1046/j.1365-2133.2001.04460.x

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