IngentaConnect Penile Kaposis sarcoma preceded by chronic penile lymphoedema

Authors: Schwartz, R.A.; Cohen, J.B.¹; Watson, R.A.²; Gascón, P.³; Ahkami, R.N.¹; Ruszczak, Z.¹; Halpern, J.⁴; Lambert, W.C.

Source: British Journal of Dermatology, Volume 142, Number 1, January 2000 , pp. 153-156(4)

Publisher: Blackwell Publishing

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Abstract:

Kaposi's sarcoma localized to the penis with striking lymphoedema is extraordinary. We report a middle-aged Haitian man who was human herpesvirus-8 seropositive, without evidence of immunosuppression or human immunodeficiency virus infection. He was first seen with Kaposi's sarcoma of 6 months duration localized to his penis, preceded by a 3-year history of chronic penile lymphoedema. His tumour regressed completely after radiotherapy. We propose that chronic lymphoedema in this patient predisposed to the development of Kaposi's sarcoma.

Keywords: human herpesvirus-8; Kaposi's sarcoma; lymphoedema; penile cancer

Document Type: Research article

DOI: 10.1046/j.1365-2133.2000.03259.x

Affiliations: 1: Dermatology, 2: Urology, 3: Hematology, 4: Radiation Oncology, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103-2714, U.S.A.

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Penile Kaposi's sarcoma preceded by chronic penile lymphoedema