IngentaConnect Glomangiosarcoma of the hip: report of a highly aggressive tumour...

Authors: Watanabe¹; Sugino¹; Saito¹; Kusakabe¹; Suzuki¹

Source: British Journal of Dermatology, Volume 139, Number 6, December 1998 , pp. 1097-1101(5)

Abstract:

Malignant glomus tumour is an extremely rare neoplasm, and only a few cases with local invasive or aggressive features have been described to date. We present a distinctive case of a malignant glomus tumour arising on the skin of the left hip of a 47-year-old woman. The primary tumour was small, with a maximum diameter of 1 cm, but 2 years after the tumour was excised, multiple lung and skin metastases appeared. Post-mortem examination also revealed widespread metastases in almost all of the visceral organs. Histological examination showed that the primary tumour was composed of a sheet-like proliferation of epithelioid round or short spindle cells surrounding small venules. In addition, there was a proliferation of long spindle cells with eosinophilic fibrillary cytoplasm, which mimicked a leiomyosarcoma. The tumour cells were intensely immunopositive for actin and vimentin but were negative for desmin. This is an exceptional case of malignant glomangiomyoma with widespread metastases, which represents a distinct variant of de novo glomangiosarcoma.

Document Type: Case report

DOI: 10.1046/j.1365-2133.1998.02574.x

Affiliations: 1: Department of Pathology, Fukushima Medical College, 1 Hikariga-oka, Fukushima, Japan, 960-12

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.16 plus tax Refund Policy

Glomangiosarcoma of the hip: report of a highly aggressive tumour with widespread distant metastases