Lymphocytic autoimmune hidradenitis, cutaneous leucocytoclastic vasculitis and primary Sjögren's syndrome

Authors: Sais1; Admella2; Fantova2; Montero3

Source: British Journal of Dermatology, Volume 139, Number 6, December 1998 , pp. 1073-1076(4)

Publisher: Blackwell Publishing

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Abstract:

We describe a 60-year-old woman with primary Sjögren's syndrome, mixed cryoglobulinaemia and cutaneous leucocytoclastic vasculitis who developed generalized hypohidrosis with a markedly decreased sweating response to pilocarpine chloride. Skin biopsies demonstrated dense peri-eccrine lymphocytic infiltrates in the lower reticular dermis, with glandular atrophy. From previous studies it is evident that although patients with Sjögren's syndrome commonly have skin dryness, a lymphocytic hidradenitis has been documented only in a few cases. The histological findings in this case support the role of autoimmune hidradenitis in the development of hypohidrosis in Sjögren's syndrome.

Document Type: Case report

DOI: 10.1046/j.1365-2133.1998.02569.x

Affiliations: 1: Departments of Dermatology, 2: Pathology and 3: Internal Medicine, Consorci Sanitari de Mataró, Lepant 13, 08301 Mataró, Barcelona, Spain

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