Management of neuropathic pain following treatment for breast cancer in the absence of recurrence: A challenge for the radiation oncologist

Author: B Clubb

Source: Australasian Radiology, Volume 48, Number 4, December 2004 , pp. 459-465(7)

Publisher: Blackwell Publishing

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Abstract:

Summary

This report reviews various management options for treatment-induced neuropathic pain in breast cancer. First-line options include tricyclic antidepressants and anticonvulsant drugs. Opioids should be prescribed according to published guidelines. Second-line treatments include lignocaine, mexiletine and ketamine. Sympatholytic therapies are available to patients with features of chronic regional pain syndrome. Anti-inflammatory agents are used for neurogenic inflammation. Surgical interventions are considered for refractory neuropathic pain. Interdisciplinary management is appropriate when persisting pain causes physical and psychosocial disabilities.

Keywords: breast cancer; neuropathic pain; radiation therapy

Document Type: Review article

DOI: 10.1111/j.1440-1673.2004.01346.x

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