Mock Circulatory System for the Evaluation of Left Ventricular Assist Devices, Endoluminal Prostheses, and Vascular Diseases

Authors: Legendre, Daniel; Fonseca, Jeison; Andrade, Aron; Biscegli, José Francisco¹; Manrique, Ricardo¹; Guerrino, Domingos¹; Prakasan, Akash Kuzhiparambil¹; Ortiz, Jaime Pinto²; Lucchi, Julio Cesar

Source: Artificial Organs, Volume 32, Number 6, June 2008 , pp. 461-467(7)

Publisher: Blackwell Publishing

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Abstract:

A new digital computer mock circulatory system has been developed in order to replicate the physiologic and pathophysiologic characteristics of the human cardiovascular system. The computer performs the acquisition of pressure, flow, and temperature in an open loop system. A computer program has been developed in Labview programing environment to evaluate all these physical parameters. The acquisition system was composed of pressure, flow, and temperature sensors and also signal conditioning modules. In this study, some results of flow, cardiac frequencies, pressures, and temperature were evaluated according to physiologic ventricular states. The results were compared with literature data. In further works, performance investigations will be conducted on a ventricular assist device and endoprosthesis. Also, this device should allow for evaluation of several kinds of vascular diseases.

Keywords: Hemodynamic performance; Mock circulatory system; Pulsatile blood flow; In vitro experiment

Document Type: Research article

DOI: 10.1111/j.1525-1594.2008.00569.x

Affiliations: 1: Institute “Dante Pazzanese” of Cardiology; 2: Department of Mechanical Engineering, Escola Politécnica, University of São Paulo;

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