IngentaConnect Development of a Novel Polyimide Hollow-fiber Oxygenator

Authors: Motohiro Niwa¹; Hiroyoshi Kawakami; Shoji Nagaoka¹; Toshiyuki Kanamori²; Kazuko Morisaku²; Toshio Shinbo²; Toshiaki Matsuda³; Kazunari Sakai³; Sunao Kubota⁴

Source: Artificial Organs, Volume 28, Number 5, May 2004 , pp. 487-495(9)

Publisher: Blackwell Publishing

Abstract:

We have developed a membrane oxygenator using a novel asymmetric polyimide hollow fiber. The hollow fibers are prepared using a dry/wet phase-inversion process. The gas transfer rates of O₂ and CO₂ through the hollow fibers are investigated in gas–gas and gas–liquid systems. The polyimide hollow fiber has an asymmetric structure characterized by the presence of macrovoids, and the outer diameter of the hollow fiber is 330 µm. It is found that the polyimide hollow-fiber oxygenator can enhance the gas transfer rates of O₂ and CO₂, and that the hollow fiber provides excellent blood compatibility in vitro and in vivo.

Keywords: Asymmetric polyimide hollow fiber; Membrane oxygenator; Gas transfer rate; Blood compatibility

Document Type: Research article

DOI: 10.1111/j.1525-1594.2004.07257.x

Affiliations: 1: Department of Applied Chemistry, Tokyo Metropolitan University, Hachioji, Tokyo 2: National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3: Dainippon Ink and Chemicals, Inc., Tokyo 4: Department of Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.16 plus tax Refund Policy