Effects of normobaric hyperoxia on haemodynamic parameters of healthy full-term parturients
Authors: Litchfield, K. N.1; Harten, J. M.2; Anderson, K. J.3; Kinsella, J.4; McGrady, E. M.3
Source: Anaesthesia, Volume 62, Number 9, September 2007 , pp. 931-935(5)
Publisher: Blackwell Publishing
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Abstract:
Summary Fifteen healthy, full-term women with singleton pregnancies were exposed to an increased FIo2 of 0.4 and their haemodynamic responses measured with a non-invasive transthoracic bio-impedance monitor. There was a mean reduction in cardiac index from 3.18 to 3.03 l.min−1.m−2 (4.7%, p = 0.004). The mean indexed systemic vascular resistance increased from 2049 to 2178 dynes.cm−5.m−2 (5.7%, p = 0.005). There were no significant changes in stroke index, heart rate or mean arterial pressure. This study demonstrates that even a moderate increase in inspired oxygen fraction has significant effects on the cardiovascular system of the term parturient.Document Type: Research article
DOI: 10.1111/j.1365-2044.2007.05150.x
Affiliations: 1: Specialist Registrar, Southern General Hospital, Department of Anaesthesia, 1345 Govan Road, Glasgow G51 4TF, UK 2: Consultant, Department of Anaesthesia, Gartnavel General Hospital, 30 Shelley Court, Great Western Road, Glasgow G12 0YN, UK 3: Consultant 4: Senior Lecturer, University of Glasgow Department of Anaesthesia, Glasgow Royal Infirmary, Queen Elizabeth Building, 10 Alexandra Parade, Glasgow G31 2ER, UK
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