IngentaConnect Gastric tonometry and prediction of outcome in the critically ill...

Authors: Gomersall, C. D.¹; Joynt, G. M.¹; Ho, K. M.¹; Young, R. J.¹; Buckley, T. A.¹; Oh, T. E.¹

Source: Anaesthesia, Volume 52, Number 7, July 1997 , pp. 619-623(5)

Abstract:

Splanchnic ischaemia is thought to be of central importance in the development of multi-organ failure and hence death in critically ill patients. It has been suggested that the arterial to gastric intramucosal pH gradient and the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood are more sensitive markers of splanchnic ischaemia than gastric intramucosal pH itself and thus should be predictors of mortality in the critically ill. We studied 62 critically ill patients within 6 h of admission to the intensive care unit and found no significant difference at 0, 12 or 24 h after admission to the study in either the arterial to gastric intramucosal pH gradient or the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood between survivors and nonsurvivors. We conclude that in contrast to gastric intramucosal pH neither the arterial to gastric intramucosal pH gradient nor the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood distinguish survivors from nonsurvivors.

Keywords: Measurement techniques; gastric tonometry. Complications; mortality

Document Type: Editorial

DOI: 10.1111/j.1365-2044.1997.146-az0150.x

Affiliations: 1: Department of Anaesthesia & Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong

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Gastric tonometry and prediction of outcome in the critically ill#Arterial to intramucosal pH gradient and carbon dioxide gradient