Computerized 2-Lead Resting ECG Analysis for the Detection of Relevant Coronary Artery Stenosis in Comparison With Angiographic Findings
Authors: Hosokawa, Joji1; Shen, Joseph T.2; Imhoff, Michael3
Source: Congestive Heart Failure, Volume 14, Number 5, September/October 2008 , pp. 251-260(10)
Publisher: Blackwell Publishing
- Free Content
- New Content
- Subscribed Content
- Free Trial Content
Abstract:
To assess the sensitivity and specificity of a new computer-enhanced resting electrocardiographic analysis device for the detection of coronary stenosis, 189 patients (aged 61.3±12.9 years, 57 women) scheduled for coronary angiography from 4 Asian centers were included in an observational study. Angiographic results were independently classified for hemodynamically relevant stenosis by 2 angiographers. The device calculated a severity score from 0 to 20. The score was significantly higher for patients with coronary stenosis (5.4±1.8 vs 1.7±2.1). The study device (cutoff 4.0) identified 73 of 77 patients with stenosis (sensitivity 94.8%, specificity 86.6%). Adjusted positive and negative predictive values were 78.4% and 97.1%, respectively (receiver operating characteristic area under the curve, 0.914 [95% confidence interval, 0.868-0.961]). Subgroup analysis showed no significant influence of sex, age, previous revascularization procedures, or participating center. The new computer-enhanced, resting electrocardiographic analysis device appears to identify patients with relevant coronary stenosis with high sensitivity and specificity. Congest Heart Fail. 2008;14:251-260. ©2008 Le JacqDocument Type: Research article
DOI: 10.1111/j.1751-7133.2008.00003.x
Affiliations: 1: From the Tokyo Heart Center, Kita-shinagawa, Shinagawa, Tokyo, Japan, 2: Premier Heart, LLC, Port Washington, NY, 3: and the Department for Medical Informatics, Biometrics and Epidemiology, Ruhr-University, Bochum, Germany
- Free Content
- New Content
- Subscribed Content
- Free Trial Content
Click here for Page Help