IngentaConnect Use of Antihypertensive Drugs during Pregnancy and Lactation

Authors: Ghanem, Firas A¹; Movahed, Assad¹

Source: Cardiovascular Drug Reviews, Volume 26, Number 1, Spring 2008 , pp. 38-49(12)

Publisher: Blackwell Publishing

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Abstract:

The decision to treat elevated arterial pressure in pregnancy depends on the risk and benefits imposed on the mother and the fetus. Treatment for mild-to-moderate hypertension during pregnancy may not reduce maternal or fetal risk. Severe hypertension, on the other hand, should be treated to decrease maternal risk. Methyldopa and β-adrenoceptor antagonists have been used most extensively. In acute severe hypertension, intravenous labetalol or oral nifedipine are reasonable choices.

Keywords: Antihypertensive drugs; β-Adrenoceptor antagonists; Labetalol; Lactation; Methyldopa; Nifedipine; Pregnancy

Document Type: Research article

DOI: 10.1111/j.1527-3466.2007.00036.x

Affiliations: 1: Section of Cardiology, Department of Medicine, The Brody School of Medicine East Carolina University, Greenville, North Carolina, USA

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