IngentaConnect Extrapleural malignant solitary fibrous tumor

Authors: Kim, Lucia¹; Paik, Ae Lan²; Chu, Young Chae¹; Park, In Suh¹; Choi, Suk Jin¹; Han, Jee Young¹; Kim, Joon Mee¹

Source: Basic and Applied Pathology, Volume 1, Number 2, June 2008 , pp. 102-106(5)

Publisher: Blackwell Publishing

Abstract:

Solitary fibrous tumor (SFT) is a ubiquitous mesenchymal neoplasm of probable fibroblastic type. Approximately 30% of SFTs arise in extrathoracic locations. The majority of SFT are benign, the malignant form accounting for 12-22%. We report a case of malignant solitary fibrous tumor in the back of a 27-year-old male patient. Grossly, the mass was well circumscribed, unencapsulated, soft to rubbery, oval shaped and measured 11.0 cm at its greatest diameter. The cut surface showed multinodular whitish-gray to tan solid appearance. Microscopically, the tumor revealed a wide spectrum of histologic features with alternating hypercellular and hypocellular areas, patternless architecture, haphazard arrangement of oval to spindle cells, branching vessels with perivascular hyalinization, frequent keloid-like collagen deposits and stromal hyalinization. Multifocal hypercellular areas revealed moderate to marked cytologic atypia and frequent mitotic figures with atypical mitoses.

Keywords: Malignant solitary fibrous tumor; extrapleural; soft tissue

Document Type: Case report

DOI: 10.1111/j.1755-9294.2008.00022.x

Affiliations: 1: Department of Pathology, Inha University Medical College, Inha University Hospital, Incheon 2: Department of Pathology, Pohang St Mary's Hospital, Pohang, Korea

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