IngentaConnect Olfactory esthesioneuroblastoma treated with orthovoltage radioth...

Authors: Ueno, H; Kobayashi, Y¹; Yamada, K²

Source: Australian Veterinary Journal, Volume 85, Number 7, July 2007 , pp. 271-275(5)

Abstract:

A 13-year-old neutered female mongrel dog presented with a 1-year history of stertorous respiration. On computed tomography examination, a mass was demonstrated in the nasal cavity. Open biopsy of the mass was performed and a diagnosis of olfactory esthesioneuroblastoma was made on histological examination. The dog was treated with orthovoltage x-ray radiation (total dose; 53 Gy given in 14 fractions over an 8 week period). Computed tomography after the twelfth irradiation revealed that tumour size had decreased. Although clinical signs were absent in the 4 months after irradiation, re-growth of the tumour was detected by radiographic evaluation and histological examination. The dog was again treated with orthovoltage x-ray radiation (total dose; 30 Gy given in three fractions over a 4-week period), however, tumour regrowth was again detected 3 months later. Clinical treatment of this tumour type has not been previously reported.

Aust Vet J 2007;85:271-275

Keywords: Dog; olfactory esthesioneuroblastoma; orthovoltage radiotherapy

Document Type: Research article

DOI: 10.1111/j.1751-0813.2007.00149.x

Affiliations: 1: Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Japan 2: Department of Clinical Veterinary Science and bPathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Japan;, Email: uehiro@cc.gifu-u.ac.jp

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Olfactory esthesioneuroblastoma treated with orthovoltage radiotherapy in a dog