@article {Longobardo:November 2006:1573-398X:397, author = "Longobardo, Guy", title = "Physiological Insights Derived from Mathematical Models of Respiration", journal = "Current Respiratory Medicine Reviews", volume = "2", year = "November 2006", abstract = "The structure of several respiratory models are reviewed and the physiological foundations of salient features are explained. The models reviewed include an early model of Cheyne-Stokes breathing, the gas stores of the body following alterations in ventilation, sleep apnea considered as instability in the respiratory control system, a neurochemical model describing effects of neural drives on breathing in respiratory control of awake people, and inclusion in the neurochemical control system a respiratory pattern generator, as a potential source of apneas. Finally, current work is described to quantify obstructive apneas, and their interdependence with central apneas and the respiratory control system.
", pages = "397-403(7)", url = "http://www.ingentaconnect.com/content/ben/crmr/2006/00000002/00000004/art00006" doi = "doi:10.2174/157339806778777249" }