@article {White:October 2006:1081-1206:446,
	author = "White, Andrew A.",
	author = "Hope, Andrew P.",
	author = "Stevenson, Donald D.",
	title = "Failure to maintain an aspirin-desensitized state in a patient with aspirin-exacerbated respiratory disease",
	journal = "Annals of Allergy, Asthma and Immunology",
	volume = "97",
	year = "October 2006",
	abstract = "Background: Aspirin desensitization is a useful therapy in patients with aspirin-exacerbated respiratory disease.<P></P> <P></P> Objective: To describe the clinical course of a man with aspirin-exacerbated respiratory disease who was unable to be desensitized to oral aspirin.<P></P> <P></P> Methods: A standard aspirin desensitization protocol was used to achieve a maximum dose of 650 mg of oral aspirin. The patient initially tolerated this dose of aspirin.<P></P> <P></P> Results: Within days of desensitization, the patient began to react to 650 mg of aspirin. Monitored challenge with this dose of aspirin led to marked decrease in forced expiratory volume in 1 second and pronounced nasal and ocular symptoms.<P></P> <P></P> Conclusions: We present a patient with classic aspirin-exacerbated respiratory disease, who despite undergoing a standard aspirin desensitization protocol was unable to maintain his desensitized state.",
	pages = "446-448(3)",
	url = "http://www.ingentaconnect.com/content/acaai/aaai/2006/00000097/00000004/art00006"
}